Tuesday, June 8, 2010

Barriers to medical advancements and the silly people that perpetuate them.

I read an article on CNN today that really cramped my crotch: Many studies great news for mice, not so much for humans

Besides the fact that it’s misleading and poorly researched, the commentary fails to disclose one very important aspect limiting the translation of bench-top biomedical research to clinical practice – profitability.

Here’s the skinny: sometimes, academic scientists can cure diseases in lab mice. Often, that’s where the story ends. Basic biomedical research infrequently becomes real-world application. There are significant reasons for this beyond those discussed in the CNN article, and they are multifold:


First, academicians aren’t particularly interested in profiting monetarily from discovery. Sounds silly, right? Unfortunately, it’s generally true. Most academics aren’t beholden to academia because they want to be rich. I’m not claiming that everyone conducting biomedical research at a university is altruistic, but if money were a pressing issue, they’d probably work in industry where they could make truckloads of it. Furthermore, it’s somewhat frowned upon in the scientific community to be all about da benjamins. I guess because researchers are supposed to be in it for the greater good, or fanatical about the integrity of our work, or something like that. Whatever the reasons, academics seldom turn their biomedical research discoveries into tangible, patentable, and marketable products (read: medicines).

Second, industry doesn’t care what academics do.
Admittedly, I’m exaggerating. Yet, ask any employee of a pharmaceutical company’s research and development team about this, and you’ll find the truth isn’t too far fetched. Industry is about profit. Drug companies have one major goal: make money. If they intend to develop a drug and market it, they require near certainty that the drug will sell. Unfortunately, diseases and/or novel therapeutic modalities that interest academics because they’re rare or understudied, usually carry the least potential profit for pharmaceutical companies – because they’re rare and understudied. Furthermore, communication between academia and industry is abysmal, preventing even those ideas which might be of mutual benefit from propagating in fertile soil. Many researchers are working on closing these gaps; still, the sharing of intellectual property between academia and industry can best be described as “throwing it over the fence.” As a result, few if any academic biomedical research discoveries are subsequently translated by industry into tangible, patentable, and marketable pharmaceuticals.

Furthermore, WE LET THIS HAPPEN. That’s right, you and me – the market. We dictate what sells based on what we buy. And for some reason, we’re more concerned about erections than we are about prostate cancer. We the people aren’t protecting ourselves from the inherent dangers of free markets in medicine. We’re content to let the market regulate itself. As a result, acne has a better shot at being cured than melanoma. There are ways out of this. The government could offer incentives to pharmaceutical companies to develop treatments for rare but fatal diseases. We could develop programs that foster discourse between academia and industry. We could invest more into therapeutic development via The National Institutes of Health…

The point is, the greatest barrier to medical advancement isn’t lack of technology - it’s misdirected motive. If we can engineer diseases in mice, trust me when I tell you that we can cure those diseases in humans. Yet, as long as we allow the healthcare market to regulate itself and let profit be the primary motive for medical advancement, we’ll get drugs that induce 4-hour erections and treat restless leg syndrome instead of cures for breast cancer and Alzheimer’s.

Tuesday, January 12, 2010

Yes, the whole world causes cancer. Sorry.

I read about cancer and conduct research towards a cure nearly everyday of my life. Little disheartens me more than the constant barrage of attacks (usually instigated by companies trying to make a profit) aimed at products which have served us valiantly for decades, now accused of being carcinogens (cancer-causing agents).

Look folks, the truth is EVERYTHING causes cancer. I can design an experiment that demonstrates any entity you can think of induces cancer in cells growing on plastic. Even water. The fact is, environmental stressors promote tumorigenesis. Yet, cancer itself is a set a complex genetic diseases – none of which can be attributed to a solitary cause. A series of unfortunate genetic events generally precedes the unchecked cell division that typically initiates tumor development. Thankfully, your body is pretty good at protecting itself from singular perturbations; nevertheless, accumulating events can overwhelm the body’s defenses, thereby causing the petrifying disease. To my dismay, people tend to focus on avoiding particular disease-causing agents, instead of taking a more beneficial holistic approach to health.

So does this mean microwaves and cell phones don’t cause cancer? If I’m perfectly honest, I have to give you an answer you probably don’t want to hear – I don’t know. In fact, the jury is still out in the cancer research community on many environmental agents purported to be cancer causing. But the axiom of consequence has previously been stated - EVERYTHING causes cancer. Hence, the best advice anyone can give you when it comes to lowering your risk for tumor development is simple: “all things in moderation.”

I know you didn’t want to hear that. You wanted me to provide a list of things you could consume or avoid to lower your cancer risks. How’s this for a list: eat right, exercise, keep away from bad things, take in more good things, place limits on everything. Maintaining a healthy lifestyle will help to reduce your risks for cancer, and ALL diseases. It really is just that simple folks… and it doesn’t take a rocket scientist (or should I say a cancer biologist) to figure it out.

Thursday, December 31, 2009

Black women are not broken, SO STOP TRYING TO FIX US!!

I get so frustrated with relationship/dating advice that places blame squarely on black women’s behavior when it comes to being single. Sure, there is always room for self-reflection, and of course there are MANY things we as women can change, but we must recognize the PRIMARY issue is not us. If we don't understand that there is a mathematical discrepancy that exists, we'll continue to try to fix something that's not even broken (which, of course, only makes the situation worse).

I'm actually hurt when I read things like: "the reason 70% of black women are single is because they’re (insert insult here)" - statements like this clearly don't acknowledge the larger problem that must be addressed. As one self-proclaimed relationship/dating advice expert submitted to me:

“Men look for three main things: great personality, respectability, and emotional availability. Many black women lack those three things which plays a huge role in why they’re single.”

Advice based on this perception is incredibly dangerous and injurious to black women. We often internalize this advice (when truly there's nothing wrong with us), and resultantly become too accommodating and emotionally available. Too many black women can speak of short “relationships” which have left them as struggling single moms, heartbroken due to infidelity, or with an STD. Too many black women are left wondering why they tolerated an undeserving man’s tomfoolery from Jump Street.

Look, the reality is, black women can self-reflect until kingdom come, it still won't make enough educated black men pop up to wife us all.

If you keep trying to fix your screen while the true problem lies within your VCR, you’re going to f*ck around and destroy your television – which was working just fine to begin with!

When it comes to black women marrying equally accomplished black men, the numbers just aren’t there. Just accept it and start broadening your horizons. If you read any dating advice geared towards black women that doesn’t ostensibly acknowledge this idea, dismiss that b*llsh*t as tomfoolery before it obliterates you from the inside out.

The main problem is we, as black women, haven't figured out how to navigate the system. We haven't figured out how to build a black man up to our level without insulting his masculinity. We haven't figured out how to love those who love us first, even if that person is not the same race as us. We haven't figured how to become patient as opposed to excessively tolerant…

I certainly don’t have all the answers - I’m still learning how to iron out those dilemmas for myself. I just pray we start searching for solutions in the right storehouses, and stop damaging self-esteem by convincing ourselves that there’s something dreadfully wrong with us, when in actuality, we’re just fine…for the most part ;-)

Tuesday, December 1, 2009

Cablinisian Privilege

Tiger Woods has the thickest veil of impenetrable presumed innocence that I've ever seen on a man who would have been a slave in 1864.

I don’t care what he calls himself, cablanasian, cablinisian – whatever the hell the term is he uses to distance himself from black – Tiger Woods would’ve been pickin’ cotton or in the kitchen snappin’ peas with the rest of us common negroes 150 years ago. Yet somehow he’s arrived at a level of success that permits him to tell police to go to hell - AND THEY LISTEN. That’s right folks, as of today, Dec. 1, 2009, Tiger Woods has not offered any details to authorities regarding the crash that occurred while driving on his property at 2:30 a.m. last week (ref). He has, however, released a miniscule amount of information to fans via his website saying he has “cuts and bruises and was ‘pretty sore’.”

Fast forward to this evening when another of Tiger’s affairs is elucidated (ref). Laughably, a response is posted on RollingOut.com titled Another Wood’s Mistress Surfaces? Why Are Women Trying to Destroy Tiger’s Marriage. Of course, the obvious question is: Why is Tiger Woods trying to destroy his own marriage? But more intriguingly, I’m completely befuddled by the propensity of the general public to presume innocence when it comes to Tiger Woods. Michael Jordan doesn’t even get that kind of red-carpet treatment.

Picture Michael Jordan dismissing authorities, telling the po po to come back later because he’s trying to sleep, and refusing to divulge the details of a crash that resulted in thousands of dollars in property damage and a potential vehicular homicide. Picture Michael Jordan walking away from it all with a $164 fine. No days. MJ’s ass woulda been up the river - old age, bald head, and all. The headlines would read: “Michael Jordan detained for further questioning in connection with mysterious crash” - and you know it. So why the discrepancy? Could it be we’re THAT color-struck?

Thursday, October 8, 2009

Talkin' 'Bout Good And Bad Hair...See If I Care

If you think hair relaxers and weaves will ultimately result in the demise of Black America, you're wrong - and overly dramatic. I would not deny that the majority of African-Americans who permed their hair with lye in the '60s did so out of desire to assimilate. But honey, this is 2009, not 1964.

Today, Black women partake in a buffet of hair options and are celebrated for exercising variety in coifing. A quick assessment of today’s high schools demonstrates relaxers do no more damage to a Black girl's identity than Nickelodeon. Our teenage girls (who frequently have authority over their hair choices) manifest a spectrum of styles. They revel in everything from 2 inch twists to waist-length weaves, and zealously delight in planning their future uncanny hair ventures.



I don’t look at a 16 year-old girl who's had her hair permed, but now chooses plaits, kinky twists, or cornrows, and conclude that a relaxer taught her self-hate, or to hate her own ethnicity.



Nonetheless, the mother who chemically modifies her child's hair at age 4 teaches a potentially more damaging lesson, one that we fail to evaluate in favor of inconsequential discussions concerning aesthetics.

Certainly, this mother realizes the damage she may cause. Still, she's willing to chemically modify her child's hair before it's sufficiently developed, without informed consent, simply to make it "more manageable". As she is willing to risk permanent destruction to her child’s crown for the benefit of not having to “deal with it", this mother inadvertently confirms, "it's ok to be lazy". Surely, there is a subconscious lesson being learned by the child here, but is that lesson primarily about aesthetics, worth, or work ethic? Arguably, the lesson includes elements of each, but which is most substantial?

This begs a greater question: what are the priorities of the Black community in this great hair debate?

Let’s face it, eventually, natural hair will be universally accepted. The reason locs and twists are not readily tolerated in corporate America today is simple - there aren't enough Blacks there to make it acceptable. Ignorance will be abrogated the moment African-Americans possess a proportionate quantity of America's power. The ultimate focus of the Black community should be arriving at that point most expeditiously.

But alas, we preferentially debate who's the “blackest”.

Truthfully, natural hair makes you no more conscious than relaxed hair indicates self-hate. Both populations are contributing to a billion-dollar a year black hair care industry that profits Asian-Americans almost exclusively.

Yet, this we don't discuss. Priorities, people!

How do we build wealth in our communities? How do we impinge upon white America’s stronghold? Is assimilation a necessary component of Black America’s transition to acceptance? These are the questions that need debating – and answering.

Honestly, hair is just hair. Individuals choose to style it in a variety of patterns, for a battery of reasons. Each time we pit naturals against relaxers, we lend credence to the notion that hair is the quintessential component of the Black woman's identity. What lesson are we teaching ourselves with this behavior? What are we proving to those who are watching us? That black people are as superficial and materialistic as they’re deemed? How ‘bout we take the steam off of that argument, and refocus our priorities on what really matters - progress.

So when it comes to good and bad hair, this blogger just doesn't care.

And now, for your viewing pleasure: Spike Lee's Good And Bad Hair. Enjoy!

Thursday, September 24, 2009

You sir, are a racist!



Ignorant racists are the most dangerous kind. No, not belligerent racists, but those who are subtly racist and fail to recognize their own prejudice. How can we ever dispose of racism if we don’t first acknowledge it? Accordingly, I composed this list, specifically for the benefit of the ignorant majority. Note (*cough* white folks): If any of these apply to you, YOU ARE WAY MORE RACIST THAN A LITTLE BIT.

Said “I’m not racist”. Everyone is at least a little racist. Defending any of your actions with this statement is merely an indication of your ignorance.
Believed “white privilege” doesn’t exist. Minorities are ~35% of the US population. Name 35 minority senators…GO!...What?! No dice? Ok, gimme 5 minority senators…Give up yet?
Worn an afro as a Halloween costume. Frankly, I’m surprised by the frequency of this behavior.

Believed Mexicans aren’t minorities. *sigh* Mexicans aren’t the majority. Not in the US. Not in the world.
Argued that Barack Obama was born in Kenya. *sigh again*. I can’t. I just can’t with this one.
Said “I have 3 black friends”. Why are we counting? Is there a limit?
Celebrated “post-racial” America. Don’t make me fall out of my chair laughing.
Given your car keys to black man in a Prada suit. If the silk tie didn’t indicate that he wasn’t the valet, the Italian leather shoes damn sure should’ve given it away.

Additionally, let me say I don’t buy into the notion that black people can’t be racist simply because as a people they lack power over the establishment. Fooey. There’s institutional racism, and there’s individual racism. Furthermore, there are gradations of racists. If you were raised in the United States of America, a nation founded on the premise that “all men were created equal” (except the skins and the coons – to hell with them), you almost certainly have at least one racist bone in your body. The question is, how racist are you? Realistically, if you don’t realize you’re at least a little racist, you’re probably A LOT.

Wednesday, September 16, 2009

Relax. ACORN is not a left-wing conspiracy. It's a hot ghetto mess.

The controversy over ACORN has reignited with many on the right outraged following Fox News coverage of a video posted on BigGovernment.com. James O’Keefe and Hannah Giles are being heralded as heroes for conducting a “sting operation” which revealed ACORN personnel on hidden camera advising a “pimp” and a “prostitute” on a mortgage application.


The ACORN staff members caught on tape were subsequently terminated. Sadly, they probably thought they were doing their jobs. Congratulations James and Hannah! You’ve discovered what many have known for years: ACORN is a hot ghetto mess. Are you surprised? I’m not.

I could have told you ACORN is unorganized and completely unreliable after they provided “housing counseling” for me during the purchase of my first home. Following my brief interaction with the organization, I was willing to sum up their service with one word: Ghetto.

So relax right-wing. ACORN is far from an undercover Obama-led conspiracy project. I can assure you, if Barack Obama had ANYTHING to do with ACORN, they’d be ten times more professional. Just ask the campaign headquarters that sprung up one block from my home a few short weeks before Election Day.

Yet James O’Keefe and Hannah Giles have managed to point out one thing: the tremendous disparity between middle America and da ‘hood. Yes, white people, they sell cigarettes out of the package in the hood. And food stamps. And unreleased movies on DVD – 2 for $15. And we “play in the fire hydrant”. And ‘hood people occasionally patronize a host of other “illegal” ventures - it’s usually called a “hook up”. Holla if ya here me.